MicroRNA-625 inhibits cell invasion and epithelial–mesenchymal transition by targeting SOX4 in laryngeal squamous cell carcinoma | Zendy

Yuan Li | Zendy; Chenjuan Tao | Zendy; Lili Dai | Zendy; Caixia Cui | Zendy; Chaohui Chen | Zendy; Honglin Wu | Zendy; Qingyu Wei | Zendy; Xuehua Zhou | Zendy

Open Access

MicroRNA-625 inhibits cell invasion and epithelial–mesenchymal transition by targeting SOX4 in laryngeal squamous cell carcinoma

Author(s) -

Yuan Li,

Chenjuan Tao,

Lili Dai,

Caixia Cui,

Chaohui Chen,

Honglin Wu,

Qingyu Wei,

Xuehua Zhou

Publication year - 2018

Publication title -

bioscience reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.938

H-Index - 77

eISSN - 1573-4935

pISSN - 0144-8463

DOI - 10.1042/bsr20181882

Subject(s) - cancer research , microrna , epithelial–mesenchymal transition , sox4 , biology , gentamicin protection assay , cell growth , western blot , cell , cancer , gene expression , metastasis , gene , promoter , genetics , biochemistry

Laryngeal squamous cell carcinoma (LSCC) is a highly aggressive malignant cancer, but the molecular mechanisms underlying its development and progression remain largely elusive. The purpose of the present study is to investigate the expression profile and functional role of microRNA-625 (miR-625) in LSCC.

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