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Induction and specification of the vertebrate ectodermal placodes: precursors of the cranial sensory organs
Author(s) -
Brugmann Samantha A.,
Moody Sally A.
Publication year - 2005
Publication title -
biology of the cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.543
H-Index - 85
eISSN - 1768-322X
pISSN - 0248-4900
DOI - 10.1042/bc20040515
Subject(s) - biology , vertebrate , sensory system , anatomy , tetrapod (structure) , neuroscience , genetics , gene , paleontology
The sensory organs of the vertebrate head derive from two embryological structures, the neural crest and the ectodermal placodes. Although quite a lot is known about the secreted and transcription factors that regulate neural crest development, until recently little was known about the molecular pathways that regulate placode development. Herein we review recent findings on the induction and specification of the pre‐placodal ectoderm, and the transcription factors that are involved in regulating placode fate and initial differentiation.