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Bioreactor systems for the production of biopharmaceuticals from animal cells
Author(s) -
Warnock James N.,
AlRubeai Mohamed
Publication year - 2006
Publication title -
biotechnology and applied biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 70
eISSN - 1470-8744
pISSN - 0885-4513
DOI - 10.1042/ba20050233
Subject(s) - biopharmaceutical , biochemical engineering , bioreactor , suspension culture , production (economics) , microbiology and biotechnology , computer science , risk analysis (engineering) , cell culture , business , biology , engineering , economics , botany , genetics , macroeconomics
The demand for biopharmaceutical products is set to see a significant increase over the next few years. As a consequence, the processes used to produce these products must be able to meet market requirements. The present paper reviews the current technologies available for animal cell culture and highlights the advantages and disadvantages of each method, while also providing details of recent case studies. Processes are described for both suspension and anchorage‐dependent cell lines.