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Artificial nerve conduits in peripheral‐nerve repair
Author(s) -
Kannan Ruben Y.,
Salacinski Henryk J.,
Butler Peter E. M.,
Seifalian Alexander M.
Publication year - 2005
Publication title -
biotechnology and applied biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 70
eISSN - 1470-8744
pISSN - 0885-4513
DOI - 10.1042/ba20040137
Subject(s) - nerve repair , medicine , peripheral nervous system , sensation , peripheral nerve , anatomy , nervous system , surgery , neuroscience , central nervous system , biology , psychiatry
Injuries to the nervous system are the result of mechanical, thermal, chemical or congenital pathologies and, if function is not restored, they lead to loss of muscle function, pain and impaired sensation. Current treatment modalities essentially coapt the two nerves ends together or place a nerve graft between the cut ends. However, clinical results have never been optimal, and therefore a quest for better options has taken place. In this review article we look at the synthetic and biomimetic options currently being tested as potential nerve grafts.