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Measurement of NADH concentration in normal and malignant human tissues from breast and oral cavity
Author(s) -
Uppal Abha,
Gupta Pradeep Kumar
Publication year - 2003
Publication title -
biotechnology and applied biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 70
eISSN - 1470-8744
pISSN - 0885-4513
DOI - 10.1042/ba20020052
Subject(s) - oral cavity , human breast , breast cancer , pathology , breast tissue , chemistry , cancer , medicine , dentistry
We report measurements of the concentration of NADH from malignant and non‐malignant sites of tissues resected from patients suffering from cancer of the breast or oral cavity. The concentration of NADH was found to be significantly higher in malignant breast‐tissue sites as compared with normal breast tissue, whereas the opposite result was obtained with malignant and normal tissues from the oral cavity. These results confirm the inferences made previously, from spectroscopic studies, and are consistent with other biochemical measurements reported in breast and oral cavity tissues.