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Local detection of pH-induced disaggregation of biocompatible micelles by fluorescence switch ON
Author(s) -
Giulia Battistelli,
Maria T. Proetto,
Alexandra MavridiPrintezi,
Matteo Calvaresi,
Alberto Danielli,
Paolo Emidio Constantini,
Claudia Battistella,
Nathan C. Gianneschi,
Marco Montalti
Publication year - 2022
Publication title -
chemical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.687
H-Index - 172
eISSN - 2041-6539
pISSN - 2041-6520
DOI - 10.1039/d2sc00304j
Subject(s) - romp , micelle , polymerization , biocompatible material , nanomedicine , copolymer , nanotechnology , chemistry , combinatorial chemistry , fluorescence , nanoparticle , biosensor , materials science , biophysics , metathesis , polymer , organic chemistry , biomedical engineering , quantum mechanics , medicine , physics , aqueous solution , biology
pH-responsive micelles disassembly, upon acidification during lysosomal uptake, leads to fluorescence switch ON. These nanoparticles are promising candidates for the design of novel stimuli-responsive drug delivery systems.

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