Open AccessAbsolute configuration determination of pharmaceutical crystalline powders by MicroED via chiral salt formation
Author(s) -
Bo Wang,
Jessica F. Bruhn,
Asmerom O. Weldeab,
Timothy S. Wilson,
Philip T. McGilvray,
Michael Mashore,
Qiong Song,
Giovanna Scapin,
Yiqing Lin
Publication year - 2022
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/d2cc00221c
Subject(s) - salt (chemistry) , absolute configuration , materials science , chemistry , nanotechnology , crystallography , stereochemistry , organic chemistry
One can confidently assign the absolute configuration of a chiral molecule using crystalline powders, via microcrystal electron diffraction (MicroED) analysis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom