
Absolute configuration determination of pharmaceutical crystalline powders by MicroED via chiral salt formation
Author(s) -
Bo Wang,
Jessica F. Bruhn,
Asmerom O. Weldeab,
Timothy S. Wilson,
Philip T. McGilvray,
Michael Mashore,
Qibin Song,
Giovanna Scapin,
Yiqing Lin
Publication year - 2022
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/d2cc00221c
Subject(s) - absolute configuration , molecule , salt (chemistry) , materials science , chemistry , absolute (philosophy) , crystallography , nanotechnology , stereochemistry , organic chemistry , philosophy , epistemology
One can confidently assign the absolute configuration of a chiral molecule using crystalline powders, via microcrystal electron diffraction (MicroED) analysis.