Open AccessA reference scale of cucurbit[7]uril binding affinities
Author(s) -
Mohammad A. Alnajjar,
Werner M. Nau,
Andréas Hennig
Publication year - 2021
Publication title -
organic and biomolecular chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 146
eISSN - 1477-0539
pISSN - 1477-0520
DOI - 10.1039/d1ob01304a
Subject(s) - affinities , binding affinities , titration , chemistry , supramolecular chemistry , combinatorial chemistry , stereochemistry , competitive binding , crystallography , organic chemistry , receptor , biochemistry , crystal structure
The binding of the macrocyclic host cucurbit[7]uril with selected guest molecules has been re-investigated to cover a large range in affinities (millimolar to femtomolar) and to set up a reference scale for future binding constant determinations.