Extensive heterogeneity of glycopeptides in plasma revealed by deep glycoproteomic analysis using size-exclusion chromatography
Author(s) -
Mayank Saraswat,
Kishore Garapati,
DongGi Mun,
Akhilesh Pandey
Publication year - 2021
Publication title -
molecular omics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.779
H-Index - 10
ISSN - 2515-4184
DOI - 10.1039/d1mo00132a
Subject(s) - glycopeptide , chromatography , size exclusion chromatography , fractionation , chemistry , biochemistry , antibiotics , enzyme
Size-exclusion chromatography facilitates simultaneous enrichment and fractionation of N -glycopeptides. Combining it with improved LC-MS/MS analysis achieves deep coverage of plasma N -glycoproteome.
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