Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein | Zendy

Rajkumar Lalji Sahani | Zendy; Thamina Akther | Zendy; Maria E. Cilento | Zendy; Andres Emanuelli Castaner | Zendy; Huanchun Zhang | Zendy; Karen A. Kirby | Zendy; Jiashu Xie | Zendy; Stefan G. Sarafianos | Zendy; Zhengqiang Wang | Zendy

Open Access

Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein

Author(s) -

Rajkumar Lalji Sahani,

Thamina Akther,

Maria E. Cilento,

Andres Emanuelli Castaner,

Huanchun Zhang,

Karen A. Kirby,

Jiashu Xie,

Stefan G. Sarafianos,

Zhengqiang Wang

Publication year - 2021

Publication title -

rsc medicinal chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.754

H-Index - 55

ISSN - 2632-8682

DOI - 10.1039/d1md00292a

Subject(s) - capsid , small molecule , metabolic stability , human immunodeficiency virus (hiv) , potency , chemistry , lead compound , chemotype , computational biology , structure–activity relationship , biochemistry , chemical space , molecular model , ligand efficiency , combinatorial chemistry , stereochemistry , drug discovery , biology , in vitro , virology , gene , ligand (biochemistry) , receptor , chromatography , essential oil

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research