Open AccessIrreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach
Author(s) -
Lewis D. Turner,
Alexander L. Nielsen,
Lucy Lin,
Sabine Pellett,
Takashi Sugane,
Margaret E. Olson,
Eric A. Johnson,
Kim D. Janda
Publication year - 2021
Publication title -
rsc medicinal chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.754
H-Index - 55
ISSN - 2632-8682
DOI - 10.1039/d1md00089f
Subject(s) - bifunctional , chemistry , neurotoxin , warhead , stereochemistry , glutathione , combinatorial chemistry , biochemistry , biophysics , enzyme , biology , engineering , aerospace engineering , catalysis
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