Open AccessUnraveling innate substrate-controlled arylation and bicyclization of 1,5-enynes with α,β conjugates: synthesis of substituted benzo[a]fluorenes
Author(s) -
Babasaheb Sopan Gore,
Junhao Lin,
Jhi-Joung Wang
Publication year - 2021
Publication title -
green chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.221
H-Index - 221
eISSN - 1463-9270
pISSN - 1463-9262
DOI - 10.1039/d1gc01248g
Subject(s) - conjugate , substrate (aquarium) , chemistry , catalysis , combinatorial chemistry , substrate specificity , solvent , surface modification , brønsted–lowry acid–base theory , organic chemistry , enzyme , biology , mathematical analysis , ecology , mathematics
Herein, we describe a novel strategy for the aromatic C–H functionalization of electron-rich arenes with 1,5-enynes anchored by conjugates, catalyzed by a Brønsted acid under metal- and solvent-free conditions.