Open AccessSesamin attenuates PM2.5-induced cardiovascular injury by inhibiting ferroptosis in rats
Author(s) -
Jingyi Ren,
Bowen Yin,
Xiang Li,
Siqi Zhu,
Jin-Liang Deng,
Yiting Sun,
Zhen-Ao Zhang,
Zihao Guo,
Huanting Pei,
Fan Zhang,
Ruiqiang Li,
Fengge Chen,
YunBao Ma
Publication year - 2021
Publication title -
food and function
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.145
H-Index - 76
eISSN - 2042-650X
pISSN - 2042-6496
DOI - 10.1039/d1fo02913d
Subject(s) - malondialdehyde , glutathione , superoxide dismutase , glutathione peroxidase , sesamin , tumor necrosis factor alpha , oxidative stress , chemistry , western blot , pharmacology , endocrinology , interleukin , antioxidant , saline , medicine , cytokine , biochemistry , enzyme , food science , gene
The present study provided the first in vivo evidence that Ses pretreatment potentially represents a novel and pragmatic therapeutic strategy to protect the cardiovascular system from damage via its anti-ferroptosis activity.