Open AccessUnderstanding alkali metal cation affinities of multi-layer guanine quadruplex DNA
Author(s) -
Celine Nieuwland,
F. Zaccaria,
Célia Fonseca Guerra
Publication year - 2020
Publication title -
physical chemistry chemical physics/pccp. physical chemistry chemical physics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.053
H-Index - 239
eISSN - 1463-9084
pISSN - 1463-9076
DOI - 10.1039/d0cp03433a
Subject(s) - guanine , chemistry , alkali metal , nucleobase , density functional theory , aqueous solution , computational chemistry , biomolecule , supramolecular chemistry , solvation , castep , g quadruplex , metal , binding energy , affinities , crystallography , chemical physics , solvent , dna , stereochemistry , organic chemistry , nucleotide , crystal structure , atomic physics , biochemistry , physics , gene
Stabilizing solvent effects and electrostatic repulsion are responsible for the constant alkali metal cation affinity in multi-layer guanine quadruplexes.