Open AccessMagnetic resonance thermometry using a GdIII-based contrast agent
Author(s) -
S. A. Amali S. Subasinghe,
Jonathan Romero,
Catherine Ward,
Matthew D. Bailey,
Donna R Zehner,
Prakrut J Mehta,
Fabio Carniato,
Maurizio Botta,
Jason T. Yustein,
Robia G. Pautler,
Matthew J. Allen
Publication year - 2021
Publication title -
chemical communications
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.837
H-Index - 333
eISSN - 1364-548X
pISSN - 1359-7345
DOI - 10.1039/d0cc06400a
Subject(s) - nuclear magnetic resonance , magnetic resonance imaging , contrast (vision) , gadolinium , materials science , resonance (particle physics) , chemistry , physics , atomic physics , optics , radiology , medicine , metallurgy
The complexes described here serve as contrast agents for magnetic resonance imaging thermometry. The complexes differentially enhance contrast between 275 and 325 K. The basis of the temperature response of the fluorinated contrast complex is the modulation of water exchange caused by trifluoromethyl groups that can be chemically controlled.