Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles | Zendy

Krzysztof M. Bąk | Zendy; Bartjan van Kolck | Zendy; Krystyna Maslowska-Jarzyna | Zendy; Panagiota Papadopoulou | Zendy; Alexander Kros | Zendy; Michał J. Chmielewski | Zendy

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Oxyanion transport across lipid bilayers: direct measurements in large and giant unilamellar vesicles

Author(s) -

Krzysztof M. Bąk,

Bartjan van Kolck,

Krystyna Maslowska-Jarzyna,

Panagiota Papadopoulou,

Alexander Kros,

Michał J. Chmielewski

Publication year - 2020

Publication title -

chemical communications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.837

H-Index - 333

eISSN - 1364-548X

pISSN - 1359-7345

DOI - 10.1039/c9cc09888g

Subject(s) - vesicle , chemistry , oxyanion , carbazole , lipid bilayer , kinetics , biophysics , membrane , biochemistry , organic chemistry , physics , quantum mechanics , catalysis , biology

A simple di(thioamido)carbazole 1 serves as a potent multispecific transporter for various biologically relevant oxyanions, such as drugs, metabolites and model organic phosphate. The transport kinetics of a wide range of oxyanions can be easily quantified by a modified lucigenin assay in both large and giant unilamellar vesicles.

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