Open AccessNovel pH-responsive and self-assembled nanoparticles based on Bletilla striata polysaccharide: preparation and characterization
Author(s) -
Junxiao Zhu,
Xuewu Guo,
Tingting Guo,
Ye Yang,
Xiuming Cui,
Jun Pan,
Yuan Qu,
Chengxiao Wang
Publication year - 2018
Publication title -
rsc advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.746
H-Index - 148
ISSN - 2046-2069
DOI - 10.1039/c8ra07202g
Subject(s) - chemistry , dynamic light scattering , nanocarriers , biocompatibility , micelle , critical micelle concentration , amphiphile , nanoparticle , nuclear chemistry , surface charge , drug delivery , biophysics , nanotechnology , copolymer , organic chemistry , materials science , polymer , aqueous solution , biology
In this investigation, innovative pH-sensitive and amphiphilic nanoparticles (NPs) were synthesized by grafting histidine (His, pH sensitive molecule) and stearic acid (SA, hydrophobic segment) onto the polysaccharides of Bletilla striata (BSP).