Novel pH-responsive and self-assembled nanoparticles based on Bletilla striata polysaccharide: preparation and characterization
Author(s) -
Junxiao Zhu,
XiaoXi Guo,
Tingting Guo,
Ye Yang,
Xiuming Cui,
Jun Pan,
Yuan Qu,
Chengxiao Wang
Publication year - 2018
Publication title -
rsc advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.746
H-Index - 148
ISSN - 2046-2069
DOI - 10.1039/c8ra07202g
Subject(s) - chemistry , dynamic light scattering , nanocarriers , biocompatibility , micelle , critical micelle concentration , amphiphile , nanoparticle , drug delivery , surface charge , nuclear chemistry , biophysics , nanotechnology , organic chemistry , copolymer , materials science , polymer , aqueous solution , biology
In this investigation, innovative pH-sensitive and amphiphilic nanoparticles (NPs) were synthesized by grafting histidine (His, pH sensitive molecule) and stearic acid (SA, hydrophobic segment) onto the polysaccharides of Bletilla striata (BSP).
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