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Astaxanthin enhances erlotinib-induced cytotoxicity by p38 MAPK mediated xeroderma pigmentosum complementation group C (XPC) down-regulation in human lung cancer cells
Author(s) -
JyhCheng Chen,
Chia-Hung Wu,
Yi-Shuan Peng,
HaoYu Zheng,
Yuan-Cheng Lin,
Peng-Fang Ma,
Ting-Chuan Yen,
TzuYing Chen,
YunWei Lin
Publication year - 2018
Publication title -
toxicology research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.709
H-Index - 31
eISSN - 2045-4538
pISSN - 2045-452X
DOI - 10.1039/c7tx00292k
Subject(s) - xeroderma pigmentosum , astaxanthin , complementation , lung cancer , cytotoxicity , cancer research , erlotinib , chemistry , p38 mitogen activated protein kinases , medicine , cancer , mapk/erk pathway , pharmacology , biochemistry , oncology , signal transduction , dna damage , gene , dna , epidermal growth factor receptor , in vitro , carotenoid , phenotype
Astaxanthin has been demonstrated to exhibit a wide range of beneficial effects that include anti-cancer and anti-inflammatory properties.

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