Open AccessNew instrumentation for large-scale quantitative analysis of components spanning a wide polarity range by column-switching hydrophilic interaction chromatography-turbulent flow chromatography-reversed phase liquid chromatography-tandem mass spectrometry
Author(s) -
Qi Song,
Yunfang Zhao,
XiaoJia Chen,
Jun Li,
Peng Li,
Yong Jiang,
Ying Wang,
Yuelin Song,
Pengfei Tu
Publication year - 2017
Publication title -
rsc advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.746
H-Index - 148
ISSN - 2046-2069
DOI - 10.1039/c7ra03788k
Subject(s) - chromatography , hydrophilic interaction chromatography , chemistry , tandem , instrumentation (computer programming) , polarity (international relations) , tandem mass spectrometry , mass spectrometry , supercritical fluid chromatography , analytical chemistry (journal) , column chromatography , high performance liquid chromatography , materials science , computer science , composite material , biochemistry , cell , operating system
New instrumentation, namely column-switching HILIC-TFC-RPLC-MS/MS, was configured for large-scale quantitative analysis of components spanning a wide polarity range in a mimic complicated sample.