Open AccessSynthetic approaches and in vitro cytotoxic evaluation of 2-acyl-3-(3,4,5-trimethoxyanilino)-1,4-naphthoquinones
Author(s) -
Jaime A. Valderrama,
Mónica Cabrera,
Julio Benites,
David Ríos,
Ricardo Inostroza-Rivera,
Giulio G. Muccioli,
Pedro Buc Calderón
Publication year - 2017
Publication title -
rsc advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.746
H-Index - 148
ISSN - 2046-2069
DOI - 10.1039/c7ra03238b
Subject(s) - naphthoquinone , in vitro , chemistry , combinatorial chemistry , stereochemistry , cytotoxic t cell , organic chemistry , biochemistry
2-Acyl-1,4-naphthoquinones react with 3,4,5-trimethoxyaniline, under aerobic conditions, to give benzophenanthridinequinone, benzocarbazole and 2-acyl-3-(3,4,5-trimethoxyanilino)-1,4-naphthoquinone derivatives.