Open AccessSilicone oil promotes amyloid-like aggregation of αB-crystallin
Author(s) -
Zhiwei Shen,
Qingyun Du,
Haozhi Lei,
Yuhui Wei,
Jun Hu,
Yi Zhang
Publication year - 2017
Publication title -
rsc advances
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.746
H-Index - 148
ISSN - 2046-2069
DOI - 10.1039/c6ra27128f
Subject(s) - silicone oil , crystallin , amyloid (mycology) , silicone , chemistry , amyloid fibril , biophysics , protein aggregation , amyloid β , biochemistry , organic chemistry , pathology , biology , medicine , inorganic chemistry , disease
Silicone oil induced changes of secondary structures of αB-crystallin (CRYAB) and promoted its aggregation into amyloid-like nanostructures.