Open AccessSensitive DNA detection using cascade amplification strategy based on conjugated polyelectrolytes and hybridization chain reaction
Author(s) -
Biqing Bao,
Jin Zhu,
L. Gong,
Jia Chen,
Yanrui Pan,
Lianhui Wang
Publication year - 2017
Publication title -
rsc advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.746
H-Index - 148
ISSN - 2046-2069
DOI - 10.1039/c6ra25882d
Subject(s) - cascade , conjugated system , dna , chain reaction , chemistry , combinatorial chemistry , polyelectrolyte , dna–dna hybridization , multiple displacement amplification , nanotechnology , polymerase chain reaction , materials science , dna extraction , photochemistry , polymer , biochemistry , gene , chromatography , organic chemistry
A novel cascade amplification strategy that combines the molecular wire effects of CPEs with the signal amplification capability of the HCR has been developed for sensitive DNA detection.