Recent developments in transition metal catalysis for quinazolinone synthesis
Author(s) -
Tracy M. M. Maiden,
Joseph P. A. Harrity
Publication year - 2016
Publication title -
organic and biomolecular chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.923
H-Index - 146
eISSN - 1477-0539
pISSN - 1477-0520
DOI - 10.1039/c6ob01402j
Subject(s) - quinazolinone , catalysis , nanotechnology , combinatorial chemistry , chemistry , biochemical engineering , materials science , organic chemistry , engineering
Quinazolinones are an important class of heteroaromatic compound, and they are prevalent in a variety of important bio-active scaffolds. Traditionally, their synthesis has been achieved via classical condensation procedures, however over recent years catalytic methodologies have emerged as effective alternatives. This review examines recent developments in the employment of catalytic approaches towards this highly important heterocyclic motif.
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