Open AccessArrangement at the nanoscale: Effect on magnetic particle hyperthermia
Author(s) -
Eirini Myrovali,
Νikolaos Μaniotis,
Antonios Makridis,
Anastasia Terzopoulou,
Vitalios Ntomprougkidis,
K. Simeonidis,
Dimitra Sakellari,
Ο. Kalogirou,
Theodoros Samaras,
Ruslan Salikhov,
Marina Spasova,
Michael Farle,
Ulf Wiedwald,
M. Angelakeris
Publication year - 2016
Publication title -
scientific reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.24
H-Index - 213
ISSN - 2045-2322
DOI - 10.1038/srep37934
Subject(s) - materials science , superparamagnetism , magnetic hyperthermia , magnetic anisotropy , particle (ecology) , magnetic nanoparticles , dipole , anisotropy , magnetic field , magnetometer , magnetic particle inspection , nanoparticle , nuclear magnetic resonance , ferromagnetism , condensed matter physics , nanotechnology , magnetization , chemistry , physics , optics , oceanography , organic chemistry , quantum mechanics , geology
In this work, we present the arrangement of Fe 3 O 4 magnetic nanoparticles into 3D linear chains and its effect on magnetic particle hyperthermia efficiency. The alignment has been performed under a 40 mT magnetic field in an agarose gel matrix. Two different sizes of magnetite nanoparticles, 10 and 40 nm, have been examined, exhibiting room temperature superparamagnetic and ferromagnetic behavior, in terms of DC magnetic field, respectively. The chain formation is experimentally visualized by scanning electron microscopy images. A molecular Dynamics anisotropic diffusion model that outlines the role of intrinsic particle properties and inter-particle distances on dipolar interactions has been used to simulate the chain formation process. The anisotropic character of the aligned samples is also reflected to ferromagnetic resonance and static magnetometry measurements. Compared to the non-aligned samples, magnetically aligned ones present enhanced heating efficiency increasing specific loss power value by a factor of two. Dipolar interactions are responsible for the chain formation of controllable density and thickness inducing shape anisotropy, which in turn enhances magnetic particle hyperthermia efficiency.