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Unearthing uric acid: An ancient factor with recently found significance in renal and cardiovascular disease
Author(s) -
Takahiko Nakagawa,
DukHee Kang,
Daniel I. Feig,
Laura Gabriela SánchezLozada,
Titte R. Srinivas,
Yuri Y. Sautin,
A. Ahsan Ejaz,
Mark S. Segal,
Richard J. Johnson
Publication year - 2006
Publication title -
kidney international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.499
H-Index - 276
eISSN - 1523-1755
pISSN - 0085-2538
DOI - 10.1038/sj.ki.5000391
Subject(s) - uric acid , disease , medicine , cardiology , intensive care medicine
Uric acid is strongly associated with cardiovascular and renal disease, but is usually not considered to have a causal role. However, recent experimental, epidemiological, and clinical studies provocatively suggest that uric acid may contribute to the development of hypertension, metabolic syndrome, and kidney disease in some patients. Clinical studies are urgently needed to examine this important possibility.

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