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Artery and vein formation: a tug of war between different forces
Author(s) -
Lin FuJung,
Tsai MingJer,
Tsai Sophia Y.
Publication year - 2007
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/sj.embor.7401076
Subject(s) - circulatory system , artery , vein , anatomy , vertebrate , blood vessel , cardiology , biology , medicine , gene , genetics
How arterial and venous fates are established is largely unknown. In the past, circulatory dynamics were thought to be the exclusive cause of arteries and veins being structurally and functionally distinct; however, growing evidence indicates that an orderly progression of molecular signals controls arterial–venous specification in the developing vertebrate vascular system.