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Survival of protozoan intracellular parasites in host cells
Author(s) -
Leirião Patrícia,
Rodrigues Cristina D,
Albuquerque Sónia S,
Mota Maria M
Publication year - 2004
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/sj.embor.7400299
Subject(s) - biology , host (biology) , intracellular parasite , intracellular , host factors , protozoan parasite , microbiology and biotechnology , virology , virus , parasite hosting , ecology , world wide web , computer science
The most common human diseases are caused by pathogens. Several of these microorganisms have developed efficient ways in which to exploit host molecules, along with molecular pathways to ensure their survival, differentiation and replication in host cells. Although the contribution of the host cell to the development of many intracellular pathogens (particularly viruses and bacteria) has been unequivocally established, the study of host‐cell requirements during the life cycle of protozoan parasites is still in its infancy. In this review, we aim to provide some insight into the manipulation of the host cell by parasites through discussing the hurdles that are faced by the latter during infection.