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Nanoparticles in Medicine: Therapeutic Applications and Developments
Author(s) -
Zhang L,
Gu FX,
Chan JM,
Wang AZ,
Langer RS,
Farokhzad OC
Publication year - 2008
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/sj.clpt.6100400
Subject(s) - nanomedicine , nanotechnology , therapeutic modalities , nanoparticle , nanomaterials , modalities , materials science , medicine , social science , sociology
Nanotechnology is the understanding and control of matter generally in the 1–100 nm dimension range. The application of nanotechnology to medicine, known as nanomedicine, concerns the use of precisely engineered materials at this length scale to develop novel therapeutic and diagnostic modalities. 1 , 2 Nanomaterials have unique physicochemical properties, such as ultra small size, large surface area to mass ratio, and high reactivity, which are different from bulk materials of the same composition. These properties can be used to overcome some of the limitations found in traditional therapeutic and diagnostic agents. Clinical Pharmacology & Therapeutics (2008); 83 , 5, 761–769. doi: 10.1038/sj.clpt.6100400