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New anticoagulants: beyond heparin, low‐molecular‐weight heparin and warfarin
Author(s) -
Bates Shan M,
Weitz Jeffrey I
Publication year - 2005
Publication title -
british journal of pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.432
H-Index - 211
eISSN - 1476-5381
pISSN - 0007-1188
DOI - 10.1038/sj.bjp.0706153
Subject(s) - warfarin , heparin , anticoagulant , medicine , venous thromboembolism , intensive care medicine , low molecular weight heparin , pharmacology , thrombosis , atrial fibrillation
The limitations of traditional anticoagulants, heparin and warfarin, have prompted the development of new anticoagulant drugs for prevention and treatment of both venous and arterial thromboembolism. After a brief review of thrombogenesis and its regulation, this paper focuses on new anticoagulant agents in more advanced stages of clinical testing. British Journal of Pharmacology (2005) 144 , 1017–1028. doi: 10.1038/sj.bjp.0706153