Open AccessCraniobot: A computer numerical controlled robot for cranial microsurgeries
Author(s) -
Leila Ghanbari,
Mathew L. Rynes,
Jia Hu,
Daniel Sousa Schulman,
Gregory Johnson,
Michael Laroque,
Gabriella Shull,
Suhasa B. Kodandaramaiah
Publication year - 2019
Publication title -
scientific reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.24
H-Index - 213
ISSN - 2045-2322
DOI - 10.1038/s41598-018-37073-w
Subject(s) - computer science , skull , microsurgery , brain tissue , biomedical engineering , anatomy , medicine , surgery
Over the last few decades, a plethora of tools has been developed for neuroscientists to interface with the brain. Implementing these tools requires precisely removing sections of the skull to access the brain. These delicate cranial microsurgical procedures need to be performed on the sub-millimeter thick bone without damaging the underlying tissue and therefore, require significant training. Automating some of these procedures would not only enable more precise microsurgical operations, but also facilitate widespread use of advanced neurotechnologies. Here, we introduce the “Craniobot”, a cranial microsurgery platform that combines automated skull surface profiling with a computer numerical controlled (CNC) milling machine to perform a variety of cranial microsurgical procedures on mice. The Craniobot utilizes a low-force contact sensor to profile the skull surface and uses this information to perform precise milling operations within minutes. We have used the Craniobot to perform intact skull thinning and open small to large craniotomies over the dorsal cortex.