Open AccessControl of meristem determinacy by trehalose 6-phosphate phosphatases is uncoupled from enzymatic activity
Author(s) -
Hannes Claeys,
Son Lang,
Xiaosa Xu,
Namiko Satoh-Nagasawa,
Andrea L. Eveland,
Alexander Goldshmidt,
Regina Feil,
Grace A. Beggs,
Hajime Sakai,
Richard G. Brennan,
John E. Lunn,
David Jackson
Publication year - 2019
Publication title -
nature plants
Language(s) - English
Resource type - Journals
ISSN - 2055-0278
DOI - 10.1038/s41477-019-0394-z
Subject(s) - meristem , trehalose , mutant , phosphatase , enzyme , phosphate , biochemistry , biology , inflorescence , microbiology and biotechnology , chemistry , botany , gene
Meristem fate is regulated by trehalose 6-phosphate phosphatases (TPPs), but their mechanism of action remains mysterious. Loss of the maize TPPs RAMOSA3 and TPP4 leads to reduced meristem determinacy and more inflorescence branching. However, analysis of an allelic series revealed no correlation between enzymatic activity and branching, and a catalytically inactive version of RA3 complements the ra3 mutant. Together with their nuclear localization, these findings suggest a moonlighting function for TPPs.