Open AccessHost dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity
Author(s) -
Rafael Ribeiro Almeida,
Raquel de Souza Vieira,
Ângela Castoldi,
Fernanda Fernandes Terra,
Amanda Campelo Lima de Melo,
Maria Cecília Campos Canesso,
Luísa Lemos,
Marcella Cipelli,
Nisha Rana,
Meire Ioshie Hiyane,
Erika L. Pearce,
Fernanda Pereira Martins,
Ana Maria Caetano Faria,
Niels Olsen Saraiva Câmara
Publication year - 2020
Publication title -
british journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.833
H-Index - 236
eISSN - 1532-1827
pISSN - 0007-0920
DOI - 10.1038/s41416-020-0915-6
Subject(s) - dysbiosis , biology , lamina propria , immunology , immune system , immunity , interleukin 17 , t cell , microbiology and biotechnology , gut flora , epithelium , genetics
Host-microbiota interactions shape T-cell differentiation and promote tumour immunity. Although IL-9-producing T cells have been described as potent antitumour effectors, their role in microbiota-mediated tumour control remains unclear.