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Early assessment of KRAS mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer
Author(s) -
Elisabetta Zulato,
Ilaria Attili,
Alberto Pavan,
Giorgia Nardo,
Paola Del Bianco,
Andrea Boscolo Bragadin,
Martina Verza,
Lorenza Pasqualini,
Giulia Pasello,
Matteo Fassan,
Fiorella Calabrese,
Valentina Guarneri,
Alberto Amadori,
Pier Franco Conte,
Stefano Indraccolo
Publication year - 2020
Publication title -
british journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.833
H-Index - 236
eISSN - 1532-1827
pISSN - 0007-0920
DOI - 10.1038/s41416-020-0833-7
Subject(s) - kras , medicine , hazard ratio , oncology , lung cancer , odds ratio , confidence interval , cancer , gastroenterology , colorectal cancer
Liquid biopsy has the potential to monitor biological effects of treatment. KRAS represents the most commonly mutated oncogene in Caucasian non-small-cell lung cancer (NSCLC). The aim of this study was to explore association of dynamic plasma KRAS genotyping with outcome in advanced NSCLC patients.

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