Open AccessAddition of an online, validated family history questionnaire to the Dutch FIT-based screening programme did not improve its diagnostic yield
Author(s) -
Victorine H. Roos,
Frank G.J. Kallenberg,
Ma van der Vlugt,
Evelien Bongers,
Cora M. Aalfs,
Patrick M. Bossuyt,
Evelien Dekker
Publication year - 2020
Publication title -
british journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.833
H-Index - 236
eISSN - 1532-1827
pISSN - 0007-0920
DOI - 10.1038/s41416-020-0832-8
Subject(s) - medicine , colonoscopy , colorectal cancer , colorectal cancer screening , family history , yield (engineering) , gold standard (test) , cancer , materials science , metallurgy
Faecal immunochemical testing (FIT) is suboptimal in detecting advanced neoplasia (AN). To increase the sensitivity and yield of a FIT-based screening programme, FIT could be combined with risk factors for AN. We evaluated the incremental yield of adding a family history questionnaire (FHQ) on colorectal cancer (CRC) and Lynch syndrome-associated tumours to the Dutch FIT-based screening programme.