Open AccessThe prognostic significance of immune microenvironment in breast ductal carcinoma in situ
Author(s) -
Michael S. Toss,
Asima Abidi,
Dorothea Lesche,
Chitra Joseph,
Sakshi Mahale,
Hugo Saunders,
Tanjina Kader,
Islam M. Miligy,
Andrew Green,
Kylie L. Gorringe,
Emad A. Rakha
Publication year - 2020
Publication title -
british journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.833
H-Index - 236
eISSN - 1532-1827
pISSN - 0007-0920
DOI - 10.1038/s41416-020-0797-7
Subject(s) - stromal cell , foxp3 , ductal carcinoma , tumor infiltrating lymphocytes , breast cancer , oncology , pathology , medicine , tumor microenvironment , cd8 , cancer research , immune system , biology , cancer , immunology
The role of different subtypes of tumour infiltrating lymphocytes (TILs) in breast ductal carcinoma in situ (DCIS) is still poorly defined. This study aimed to assess the prognostic significance of B and T lymphocytes and immune checkpoint proteins expression in DCIS.