Open AccessDetection and prognostic role of heterogeneous populations of melanoma circulating tumour cells
Author(s) -
Carlos Aya-Bonilla,
Michael Morici,
Xin Hong,
Ashleigh C. McEvoy,
Ryan J. Sullivan,
James B. Freeman,
Leslie Calapre,
Muhammad A. Khattak,
Tarek Meniawy,
Michael Millward,
Mel Ziman,
Elin S. Gray
Publication year - 2020
Publication title -
british journal of cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.833
H-Index - 236
eISSN - 1532-1827
pISSN - 0007-0920
DOI - 10.1038/s41416-020-0750-9
Subject(s) - circulating tumor cell , melanoma , digital polymerase chain reaction , tumour heterogeneity , medicine , biomarker , oncology , cancer research , cancer , pathology , biology , gene , metastasis , polymerase chain reaction , genetics
Circulating tumour cells (CTCs) can be assessed through a minimally invasive blood sample with potential utility as a predictive, prognostic and pharmacodynamic biomarker. The large heterogeneity of melanoma CTCs has hindered their detection and clinical application.