Open AccessNASH Leading Cause of Liver Transplant in Women: Updated Analysis of Indications For Liver Transplant and Ethnic and Gender Variances
Author(s) -
Mazen Noureddin,
Aarshi Vipani,
Catherine Bresee,
Tsuyoshi Todo,
Irene Kim,
Naim Alkhouri,
Veronica Wendy Setiawan,
Tram T. Tran,
Walid Ayoub,
Shelly C. Lu,
Andrew S. Klein,
Vinay Sundaram,
Nicholas N. Nissen
Publication year - 2018
Publication title -
the american journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.907
H-Index - 252
eISSN - 1572-0241
pISSN - 0002-9270
DOI - 10.1038/s41395-018-0088-6
Subject(s) - medicine , hepatocellular carcinoma , liver transplantation , chronic liver disease , hepatitis c , liver disease , hepatitis c virus , alcoholic liver disease , hepatology , gastroenterology , transplantation , cirrhosis , immunology , virus
Chronic infection with hepatitis C virus (HCV) was previously the leading indication for liver transplant (LT) in the United States. However, since 2014 the use of direct-acting antivirals (DAAs) has decreased the chronic HCV burden, while the prevalence of nonalcoholic steatohepatitis (NASH) has risen substantially through the last decade. Both gender and ethnic disparities in indications for LT have been shown in the past but no data on this have been reported since the implementation of DAAs.