Open AccessPediatric ECMO: unfavorable outcomes are associated with inflammation and endothelial activation
Author(s) -
Sherrill D Caprarola,
Derek K. Ng,
Matthew S. Carroll,
Aylin Tekes,
Ryan J. Felling,
Cynthia F. Salorio,
Reem Almuqati,
Jamie Mc Elrath Schwartz,
Allen D. Everett,
Melania M. Bembea
Publication year - 2021
Publication title -
pediatric research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 150
eISSN - 1530-0447
pISSN - 0031-3998
DOI - 10.1038/s41390-021-01817-8
Subject(s) - medicine , endothelial activation , proinflammatory cytokine , extracorporeal membrane oxygenation , plasminogen activator inhibitor 1 , tissue plasminogen activator , plasminogen activator , thrombomodulin , inflammation , thrombus , immunology , gastroenterology , platelet , thrombin
Inflammatory and endothelial activation responses during extracorporeal membrane oxygenation (ECMO) support in children are poorly understood. In this study, we aimed to determine if circulating inflammatory, endothelial activation, and fibrinolytic markers are associated with mortality and with neurologic outcomes in children on ECMO.