Open AccessGenetic determinants of metabolic biomarkers and their associations with cardiometabolic traits in Hispanic/Latino adolescents
Author(s) -
Daeeun Kim,
Anne E. Justice,
Geetha Chittoor,
Estela Blanco,
Raquel Burrows,
Mariaelisa Graff,
Annie Green Howard,
Yujie Wang,
Rebecca Rohde,
Victoria L. Buchanan,
V. Saroja Voruganti,
Marcio Almeida,
Juan M. Peralta,
Donna M. Lehman,
Joanne E. Curran,
Anthony G. Comuzzie,
Ravindranath Duggirala,
John Blangero,
Cecilia Albala,
José Luís Santos,
Bárbara Ángel,
Betsy Lozoff,
Sheila Gahagan,
Kari E. North
Publication year - 2021
Publication title -
pediatric research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 150
eISSN - 1530-0447
pISSN - 0031-3998
DOI - 10.1038/s41390-021-01729-7
Subject(s) - adiponectin , ghrelin , leptin , biomarker , medicine , adipokine , insulin resistance , endocrinology , insulin , biology , obesity , genetics , hormone
Metabolic regulation plays a significant role in energy homeostasis, and adolescence is a crucial life stage for the development of cardiometabolic disease (CMD). This study aims to investigate the genetic determinants of metabolic biomarkers-adiponectin, leptin, ghrelin, and orexin-and their associations with CMD risk factors.