Open AccessMaternal dietary fat intake and the risk of congenital heart defects in offspring
Author(s) -
R. Thomas Collins,
Wei Yang,
Suzan L. Carmichael,
Elijah H. Bolin,
Wendy N. Nembhard,
Gary M. Shaw
Publication year - 2020
Publication title -
pediatric research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 150
eISSN - 1530-0447
pISSN - 0031-3998
DOI - 10.1038/s41390-020-0813-x
Subject(s) - offspring , medicine , pregnancy , dietary fat , logistic regression , physiology , population , obstetrics , endocrinology , environmental health , biology , genetics
Fatty acids are crucial in embryologic development, including cardiogenesis. The impact of maternal periconceptional dietary fat intake on the risk of congenital heart defects (CHDs) has not been clearly elucidated. We hypothesized that maternal dietary fat intake during pregnancy is associated with risk of CHDs in offspring.