Open AccessEarly pediatric chronic kidney disease is associated with brain volumetric gray matter abnormalities
Author(s) -
Matthew A. Solomon,
Ellen van der Plas,
Kathleen E. Langbehn,
Marci Novak,
Jordan L. Schultz,
Timothy R. Koscik,
Amy L. Conrad,
Patrick D. Brophy,
Susan L. Furth,
Peg Nopoulos,
Lyndsay A. Harshman
Publication year - 2020
Publication title -
pediatric research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 150
eISSN - 1530-0447
pISSN - 0031-3998
DOI - 10.1038/s41390-020-01203-w
Subject(s) - neurocognitive , brain size , medicine , magnetic resonance imaging , neuroimaging , white matter , atrophy , pathology , pediatrics , cognition , radiology , psychiatry
The impact of pediatric chronic kidney disease (pCKD) on the brain remains poorly defined. The objective of this study was to compare brain morphometry between children with early-stage pCKD and typically developing peers using structural magnetic resonance imaging (MRI).