Open AccessCX3CR1 as a respiratory syncytial virus receptor in pediatric human lung
Author(s) -
Christopher Anderson,
Chin Yi Chu,
Qian Wang,
Jared A. Mereness,
Yue Ren,
Kathy Donlon,
Soumyaroop Bhattacharya,
Ravi Misra,
Edward E. Walsh,
Gloria Pryhuber,
Thomas J. Mariani
Publication year - 2019
Publication title -
pediatric research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 150
eISSN - 1530-0447
pISSN - 0031-3998
DOI - 10.1038/s41390-019-0677-0
Subject(s) - cx3cr1 , lung , receptor , chemokine , immunology , biology , virus , respiratory system , chemokine receptor , virology , in situ hybridization , medicine , gene expression , immune system , gene , biochemistry , anatomy
Data on the host factors that contribute to infection of young children by respiratory syncytial virus (RSV) are limited. The human chemokine receptor, CX3CR1, has recently been implicated as an RSV receptor. Here we evaluate a role for CX3CR1 in pediatric lung RSV infections.