Open AccessDelivery-based criteria for empiric antibiotic administration among preterm infants
Author(s) -
Samuel J. Garber,
Miren B. Dhudasia,
Dustin D. Flannery,
Molly Passarella,
Karen M. Puopolo,
Sagori Mukhopadhyay
Publication year - 2020
Publication title -
journal of perinatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.912
H-Index - 94
eISSN - 1476-5543
pISSN - 0743-8346
DOI - 10.1038/s41372-020-00784-y
Subject(s) - medicine , guideline , low birth weight , antibiotics , incidence (geometry) , pediatrics , cohort , cohort study , gestational age , obstetrics , pregnancy , physics , optics , pathology , biology , microbiology and biotechnology , genetics
Determine impact of using delivery criteria to initiate antibiotics among very low birth weight (VLBW) and extremely low birth weight (ELBW) infants. STUDY DESIGN: Single site cohort study from 01/01/2009 to 01/31/2020. After 04/2017, infants delivered by Cesarean section, without labor or membrane rupture were categorized as low-risk for early-onset infection and managed without empiric antibiotics. We determined effect of this guideline by pre-post, and interrupted time-series analyses.