Open AccessGenetic variations in adiponectin levels and dietary patterns on metabolic health among children with normal weight versus obesity: the BCAMS study
Author(s) -
Гэ Ли,
Ling Zhong,
Lanwen Han,
Yonghui Wang,
Bo Li,
Dongmei Wang,
Yanglu Zhao,
Yu Li,
Qian Zhang,
Lü Qi,
John R. Speakman,
Steven M. Willi,
Ming Li,
Shan Gao
Publication year - 2021
Publication title -
international journal of obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.663
H-Index - 225
eISSN - 1476-5497
pISSN - 0307-0565
DOI - 10.1038/s41366-021-01004-z
Subject(s) - adiponectin , metabolic syndrome , overweight , medicine , obesity , endocrinology , childhood obesity , adipose tissue , cohort , physiology , insulin resistance
Adiponectin represents an important link between adipose tissue dysfunction and cardiometabolic risk in obesity; however, there is a lack of data on the effects of adiponectin-related genetic variations and gene-diet interactions on metabolic disorders in children. We aimed to investigate possible interactions between adiponectin-related genetic variants and habitual dietary patterns on metabolic health among children with normal weight versus overweight/obesity, and whether these effects in childhood longitudinally contribute to metabolic risk at follow-up.