Open AccessOpinion: The Pharmacometrics of Infectious Disease
Author(s) -
Davies GR,
Hope W,
Khoo S
Publication year - 2013
Publication title -
cpt: pharmacometrics and systems pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 37
ISSN - 2163-8306
DOI - 10.1038/psp.2013.46
Subject(s) - infectious disease (medical specialty) , clinical pharmacology , medicine , personalized medicine , drug development , expert opinion , disease , intensive care medicine , data science , drug , bioinformatics , pharmacology , computer science , biology , pathology
The application of pharmacometric principles to the treatment of infectious diseases must address important biological issues across the diversity of pathogenic organisms. Recent applications of pharmacometric tools in this therapeutic area have had important translational impact not only in drug development but on real‐world clinical practice. The fruitful fusion of preclinical and population methodologies promises increasingly personalized and mechanistic approaches. CPT: Pharmacometrics & Systems Pharmacology (2013) 2, e70; doi: 10.1038/psp.2013.46 ; published online 28 August 2013