z-logo
open-access-imgOpen Access
Modeling and Simulation at the Interface of Nonclinical and Early Clinical Drug Development
Author(s) -
Visser SAG,
Manolis E,
Danhof M,
Kerbusch T
Publication year - 2013
Publication title -
cpt: pharmacometrics and systems pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 37
ISSN - 2163-8306
DOI - 10.1038/psp.2013.3
Subject(s) - drug development , session (web analytics) , pharmacology , agency (philosophy) , drug , operations research , medicine , computer science , engineering , sociology , world wide web , social science
The role of modeling and simulation (M&S) in early drug development was discussed in a break out session of the European Medicines Agency/European Federation of Pharmaceutical Industries and Associations (EMA/EFPIA) M&S workshop held in December 2011 in London, UK. The discussions were focused on two themes: (i) M&S in nonclinical and early clinical drug development and (ii) M&S for first‐in‐human (FIH) dose selection. Illustrative case studies were presented and links are listed in Table 1. Common objectives and next steps were identified, discussed, and agreed. CPT: Pharmacometrics & Systems Pharmacology (2013) 2, e30; doi: 10.1038/psp.2013.3 ; advance online publication 27 February 2013

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here