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Impact of Surgically Induced Weight Loss on Cardiovascular Autonomic Function: One‐year Follow‐up
Author(s) -
Maser Raelene E.,
Lenhard M. James,
Irgau Isaias,
Wynn Gail M.
Publication year - 2007
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1038/oby.2007.554
Subject(s) - medicine , weight loss , autonomic function , diaphragmatic breathing , valsalva maneuver , diabetes mellitus , laparoscopic adjustable gastric banding , obesity , surgery , heart rate , cardiology , type 2 diabetes , blood pressure , gastric bypass , heart rate variability , endocrinology , alternative medicine , pathology
Objective: To determine the impact of surgically induced weight loss on cardiovascular autonomic function in subjects with severe obesity and examine whether the effect was comparable for persons with and without diabetes. Research Methods and Procedures: Twenty‐six severely obese individuals (BMI = 48 ± 7 kg/m 2 ) underwent bariatric surgery (laparoscopic Roux‐en‐Y gastric bypass, n = 21; laparoscopic adjustable gastric banding, n = 5). Cardiovascular autonomic function (heart rate variation during deep breathing and the Valsalva maneuver) was assessed before and 6 and 12 months after surgery. Results: Twelve months after bariatric surgery, there was a 28% decrease in BMI. There was an increase in all parasympathetic indices of autonomic function (all assessment modalities, p < 0.05) with weight loss. The amount of improvement from baseline for all measures of autonomic function did not differ for those with or without diabetes. Discussion: Surgically induced weight loss 12 months after surgery has a favorable effect on cardiovascular autonomic function in severely obese individuals with and without diabetes.