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Circadian Rhythms and the Regulation of Metabolic Tissue Function and Energy Homeostasis
Author(s) -
Zvonic Sanjin,
Floyd Z. Elizabeth,
Mynatt Randall L.,
Gimble Jeffrey M.
Publication year - 2007
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1038/oby.2007.544
Subject(s) - circadian rhythm , adipose tissue , biology , homeostasis , function (biology) , obesity , glucose homeostasis , endocrinology , energy homeostasis , metabolic syndrome , medicine , neuroscience , bioinformatics , insulin resistance , microbiology and biotechnology
Circadian oscillators play an indispensable role in the coordination of physiological processes with the cyclic changes in the physical environment. A significant number of recent clinical and molecular studies suggest that circadian biology may play an important role in the regulation of adipose and other metabolic tissue functions. In this discussion, we present the hypothesis that circadian dysfunction may be involved in the pathogenesis of obesity, type 2 diabetes, and the metabolic syndrome.