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Intramyocellular Lipid Content in Human Skeletal Muscle
Author(s) -
SchrauwenHinderling Vera B.,
Hesselink Matthijs K.C.,
Schrauwen Patrick,
Kooi Marianne Eline
Publication year - 2006
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1038/oby.2006.47
Subject(s) - skeletal muscle , medicine , endocrinology , adipose tissue , glycogen , chemistry , insulin sensitivity , fatty acid , insulin resistance , insulin , biology , biochemistry
Fat can be stored not only in adipose tissue but also in other tissues such as skeletal muscle. Fat droplets accumulated in skeletal muscle [intramyocellular lipids (IMCLs)] can be quantified by different methods, all with advantages and drawbacks. Here, we briefly review IMCL quantification methods that use biopsy specimens (biochemical quantification, electron microscopy, and histochemistry) and non‐invasive alternatives (magnetic resonance spectroscopy, magnetic resonance imaging, and computed tomography).