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Adult Obesity and Number of Years Lived with and without Cardiovascular Disease
Author(s) -
Silva M. Carolina Pardo,
Laet Chris,
Nusselder Wilma J.,
Mamun Abdulah A.,
Peeters Anna
Publication year - 2006
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1038/oby.2006.144
Subject(s) - medicine , obesity , life expectancy , myocardial infarction , stroke (engine) , disease , framingham heart study , confidence interval , diabetes mellitus , body mass index , demography , pediatrics , gerontology , framingham risk score , endocrinology , population , environmental health , mechanical engineering , sociology , engineering
Objective: To determine the differences in number of years lived free of cardiovascular disease (CVD) and number of years lived with CVD between men and women who were obese, pre‐obese, or normal weight at 45 years of age. Research Methods and Procedures: We constructed multistate life tables for CVD, myocardial infarction, and stroke, using data from 2551 enrollees (1130 men) in the Framingham Heart Study who were 45 years of age. Results: Obesity and pre‐obesity were associated with fewer number of years free of CVD, myocardial infarction, and stroke and an increase in the number of years lived with these diseases. Forty‐five‐year‐old obese men with no CVD survived 6.0 years [95% confidence interval (CI), 4.1; 8.1] fewer than their normal weight counterparts, whereas, for women, the difference between obese and normal weight subjects was 8.4 years (95% CI: 6.2; 10.8). Obese men and women lived with CVD 2.7 (95% CI: 1.0; 4.4) and 1.4 years (95% CI: −0.3; 3.2) longer, respectively, than normal weight individuals. Discussion: In addition to reducing life expectancy, obesity before middle age is associated with a reduction in the number of years lived free of CVD and an increase in the number of years lived with CVD. Such information is paramount for preventive and therapeutic decision‐making by individuals and practitioners alike.